Nail Polish Remover: Acetone or Non-Acetone

What exactly is the difference?

Acetone is a chemical that can be used in nail polish.  It is often considered a strong ingredient that can be harsh on nails.  People who have fake nails do not want to use nail polish with acetone in it because it can wear away at them, or even remove them.  I prefer nail polish remover with acetone in it because it takes of the polish much quicker.  I have to use less remover, therefore my nails don't get as dried out.  It is also helpful when removing sparkle nail polish. 

So non-acetone remover is less harsh on nails and better for fake ones, but can be not as strong while acetone remover is harsher but works better?

Is that the only difference between the two?